Abbott Bets Big on Cancer: Is Exact Sciences Worth the $21 Billion Price Tag?
Abbott's move to acquire Exact Sciences for a cool $21 billion has certainly turned heads. Exact Sciences, best known for its Cologuard noninvasive colorectal cancer screening test, is projected to bring in over $3 billion in revenue this year. Abbott clearly sees a long-term play in cancer diagnostics, with CEO Robert Ford stating it reflects their view on "medical need and clinical need across the global healthcare markets." (A view, it's worth noting, that comes with a hefty price tag).
But let's dissect the numbers. Abbott anticipates that this acquisition will boost their total diagnostics sales to over $12 billion annually. That's a significant jump, but is it justified? The cancer screening and precision oncology diagnostics market is estimated at $60 billion in the U.S. alone. If Abbott can capture a substantial piece of that pie, the investment could pay off.
However, there's always a "but," isn't there? Exact Sciences also carries an estimated $1.8 billion in debt, which Abbott will absorb. That's a considerable liability. The acquisition is expected to be immediately accretive to Abbott's revenue growth and gross margin. "Accretive" is the key word here – it sounds good, but what's the actual percentage we are talking about?
Beyond Cologuard, Exact Sciences boasts other products, including the Oncotype DX breast cancer test and liquid biopsy tests for multi-cancer early detection and molecular residual disease testing. These are the high-growth potential areas. It is likely that Abbott is not just buying Cologuard, but the future potential of these pipelines.

TD Cowen analyst Joshua Jennings suggests that acquiring Exact Sciences could revitalize Abbott’s diagnostics business and potentially return the segment to pre-pandemic growth rates. That's a bold claim. The pandemic skewed everything. Are we really using pre-pandemic figures as a reliable benchmark anymore?
Leerink Partners analyst Puneet Souda calls the transaction a "sector defining event" and believes it validates the diagnostics sector and the central lab business model. It's certainly the largest medtech acquisition this year, but does size equate to validation? Or does it simply mean Abbott had the deepest pockets? I've looked at hundreds of these acquisitions, and this level of exuberance always makes me a little nervous.
One thing that's not explicitly stated is the competitive landscape. What other players are vying for dominance in this space? How does Exact Sciences' technology compare? These are crucial questions that investors need answered before fully embracing this deal. While the PR is optimistic, the devil is always in the details, and the details, in this case, remain somewhat obscured.
Abbott is betting big on cancer diagnostics. The acquisition of Exact Sciences is a bold move, no doubt. But is it a smart one? Only time—and the balance sheets—will tell. At $105 per share for Exact Sciences shareholders, the deal is undoubtedly a win for them. But for Abbott, the pressure is on to deliver a return on this massive investment. Abbott to acquire Exact Sciences for about $21B
The $21 billion price tag raises eyebrows. Abbott's move is either a visionary leap or a costly miscalculation. The market will be the ultimate judge.